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Medical Cases

MAY 2016

Dr. Jyoti Jadhav

Star Imaging and Research Centre Medical case list

HISTORY

Case Courtesy:
Dr. Rakesh Neve
  • 37 year old female patient presented with swelling on the right side of face and right sided nasal obstruction.

FINDING & CONCLUSION

  • Large lobulated avidly enhancing sinonasal mass centred on the right maxillary sinus with extensive adjacent expansile bony thinning and erosions
  • The mass bulges into the floor of the orbit, nasal cavity as well as into the premaxillary soft tissues, and retroantral fat on right side. No obvious intraconal extension or perineural extension of the pathology seen. Retroobstructive changes are noted in the right-sided paranasal sinuses surrounding the mass
  • Right sided maxillary expansile mass with a multilocular appearance and extension into the orbit, ethmoid sinus and into pterygopalatine fossa on right side. Also there is erosion of greater and lesser palatine foramina on right side
  • Central giant cell granuloma
  • Also known as giant cell reparative cyst/granuloma
  • Most common sites include: Maxilla and mandible
  • Rare site: Long bones of hands and feet
  • Strikingly occurs more commonly on the right than left side
  • Age: 2nd-3rd decade
  • F >M
  • Etiology: The lesion increase by accumulation of tissue which is produced by slow, minute, continuous hemorrhages of multicentric nature due to trauma and some defect in the capillaries.
  • Histopathology: Composed of fibroblastic cells and giant cells. The giant cells are variably distributed and show focal clustering around areas of hemorrhage. Woven and lamellar bone is present. No cellular atypia.
  • Localised lesion: Curettage of lesion
  • Extensive lesion: Partial maxillectomy/mandibulectomy
  • Medical management: as an adjunct to surgery; treatment with steroids and calcitonin which inhibits osteoclastic activity